Studies Completed in 2010: Regional, National and International Studies Recruiting in East London
NIHR Portfolio
The aetiology and prevention of in-patient suicide.
UK CRN ID no. 5656
R&D ref. no K0810/1
Chief Investigator: Professor Louis Appleby - 0161 275 0714
To identify the antecedents of suicide in 3 psychiatric in-patient groups:
- Patients who absconded prior to suicide
- Patients who were under observation at the time of suicide
- Patients who were on agreed leave at the time of suicide
The aim of the study is to inform suicide prevention strategies in these high-risk patient groups.
An Evaluation of the Effectiveness of Different Treatment Pathways and Service Provisions for Adolescents with Eating Disorders.
UK CRN ID no. 4523
R&D ref. no. K0808/1
Chief Investigator: Dr Ivan Eisler - 020 7848 0199 - i.eisler@iop.kcl.ac.uk
Local point of contact: Dr Navina Evans - 02075406789 - navina.evans@eastlondon.nhs.uk
The primary objective of this research is to assess the impact of the availability of specialist outpatient services for adolescents with eating disorders on the need for inpatient treatment and the cost of treatment provision to the NHS.
Case control studies of psychiatric in-patients and those discharged
UK CRN no. 6605
R&D ref. no. K0908/1
Chief Investigator: Professor Nav Kapur - 01612750737 - nav.kapur@manchester.ac.uk
There are three research questions:
- What are the characteristics of early admission and recently discharged suicide cases?
- What are the specific risk factors for suicide occurring early in admission?
- What are the specific risk factors for suicide occurring early on in the post-discharge period?
Support at home interventions to enhance life in dementia (SHIELD) - Maintenance Cognitive Stimulation Therapy: A Single blind, multi-centre, randomised controlled trial of maintenance CST vs. CST for Dementia.
UK CRN ID no. 4929
R&D ref. no. S0910/4
Chief Investigator: Professor Martin Orrell - 01277 302736 – m.orrell@ucl.ac.uk
Are Maintenance Cognitive Stimulation Therapy Groups more effective in the long term that Cognitive Stimulation Therapy alone?
What is the incremental cost-effectiveness of maintenance CST groups, compared with that of CST groups alone, in ameliorating the quality of life and improving cognition of people with dementia?
Evaluation of new models improving access to psychological therapies
UK CRN ID no. 4651
R&D ref. no. N0708/2
Chief Investigator: Professor Glenys Parry - 0114 2220856 - G.D.Parry@sheffield.ac.uk
Is providing improved access to psychological therapies at two national pilot sites cost effective when compared to providing the existing level of psychological services at comparable sites?
More information: www.shef.ac.uk/cpsr/projects/iapt.html
A study to investigate the prevalence of mental illness among victims of homicide and the demographic, clinical and criminological characteristics of victims.
UK CRN ID no: 5658
R&D ref. no. K0809/1
Chief Investigator: Professor Jenny Shaw - 01772406631 - cathy.farrer@lancashirecare.nhs.uk
The current study aims to extend the Homicide Inquiry data collection processes to include victims of homicide. This will be conducted on a national basis and will enable us to establish the number of people under mental health care who are the victims of homicide and to identify the clinical, criminological and social antecedents leading up to the homicide.
Own Account
Improving Access to Psychological Therapy: health consumption
R&D ref. no. S0903/1
Chief Investigator: Dr. Simon de Lusignan - 020 8725 5661 - slusigna@sgul.ac.uk
Local point of contact: Dr Ben Wright - 02085485503 - ben.wright@eastlondon.nhs.uk
The study’s principal objectives are:
- Compared the Office of National Statistics' (ONS) estimated prevalence of psychological illness in the community with that presenting to general practice, and with that referred to new pathways for psychological therapy in the reconfigured services in the 2 demonstration sites.
- Compare the consumption of health service resources as recorded in GP computer systems and SUS (Secondary Uses Services) data for people who have been referred to the IAPT programme with matched controls who were not referred.
- Make recommendations as to how data quality might be improved in the IAPT and primary care databases.
The study also aims to contribute to the development of technical and governance processes in de-identifying and linking routinely collected healthcare databases to support service planning and service evaluation in general: -
- Specifically, we will be working with Sapior’s technology, data privacy experts, to develop a rigorous process of de-identification that is acceptable to GP practices, lead practitioners of the IAPT Programme, and Primary Care Trusts (PCTs) for the 2 demonstration sites practices. The de-identification process will be described in more details in later sections.
- Through the use of unique pseudonyms, the project will achieve linkage of the relevant data fields of the 3 existing databases: IAPT Programme data, clinical information held in GP practice information systems and SUS data to create an anonymised dataset for analysis.
Cultural Consultancy Intervention in Forensic Settings
R&D ref. no. S1001/5
Chief Investigator: Dr. David Ndegwa -- 020 3228 6219 -- charlotte.mclaughlin@slam.nhs.uk
Local point of contact: Dr Neil Boast - 020 8510 2436 – Neil.Boast@eastlondon.nhs.uk
Can we design an intervention based on cultural narratives and other information from cultural consultation which will change the experience of service users in forensic psychiatric settings; particularly where the current conflictual experience is related to the patients' culture?
The main purpose of this study is to improve the experience of patients in forensic psychiatric settings. We will do this by adapting an anthropologically informed cultural consultancy and conflict resolution intervention, previously developed for use in general psychiatry. We are adapting it so that it can be used in forensic medium secure settings. We aim to establish the wider feasibility of the intervention and provide first estimates of likely effect sizes, to inform a future multisite cluster randomised control trial. The approach used is informed by the MRC framework for trials of complex interventions. The project covers phase I and phase II of this MRC framework.
Pregnancy and Substance Misuse: A Study of Maternity Services
R&D ref. no. K0808/2
Chief Investigator: Dr A.W. Stevens – 01227827304 - A.W.Stevens@kent.ac.uk
Local point of contact: Dr P.C. Radcliffe - 01227 823162 - P.C.Radcliffe@kent.ac.uk
How are pregnant substance-misusing women and their foetuses assessed, monitored and treated?
How do substance misusing women describe their response to the treatment they are offered and to the supervision and surveillance of their pregnancies?
Educational
Staff perceptions of service users who use cannabis
R&D ref. no. S1001/4
Chief Investigator: Miss Louise Blurton – 0208 2234174 - l.blurton@uel.ac.uk
This research aims to address the following principle research question:
What accounts do mental health professionals give in relation to service users who have a diagnosis of psychosis and who use cannabis?
The secondary research questions the research aims to address are:
- How are mental health professionals’ accounts influenced by factors such as age, ethnicity, professional discipline, preferred model of psychosis and seniority?
- How do these influences impact on mental health professionals’ views on how to intervene (e.g. abstaining from the drug, using small amounts safely) when service users with a diagnosis of psychosis are using cannabis?
- In relation to treatment and intervention, how do mental health professionals feel they can help this group of service users?
Therapists' experiences of working psychotherapeutically in dementia
R&D ref. no. K1003/2
Chief Investigator: Miss Philippa Blythe - PMB0035@londonmet.ac.uk
The principle research question is how do psychological therapists experience their psychotherapeutic work with individuals with dementia?
Secondary research question: how do psychological therapists experience the therapeutic processes involved, such as the therapeutic relationship, when working with individuals with dementia?
Living with a parent with mental health needs: What children say
R&D ref. no. S0909/3
Chief Investigator: Ms Liana Hadleigh – u0731069@uel.ac.uk
How do children talk about having a parent with mental health problems and the impact it has on their lives?
Do children identify positive aspects to having a parent with mental health problems?
Exploring change processes in systemic psychotherapy with children with conduct disorder and their families
R&D ref. no. K0605/6
Chief Investigator: Ms Luisa E. Marin-Avellan - 0781-783 3742 - lavellan@sgul.ac.uk
Sub-study 1: To develop a procedure that combines the use of the SWAP-200 and the HCR-20 to systematise and organise clinical judgements of violence risk making them more reliable and valid with forensic community patients who have a diagnosis of personality disorder and a history of violence.
- To investigate the contribution of hitherto understudied personality factors to the risk of violent behaviour;
- To use the SWAP-200 to design personality prototypes of violent offenders;
- To find out clinicians's views on the practical use and clinical utility of the SWAP-200 as a diagnostic instrument for PD.
Sub-study 2: To investigate service users' views on factors that increase the risk of violent behaviour. To compare users and clinicians' views on factors that increase the risk of violence.
Young people's experiences of living with a parent with psychosis.
R&D ref. no. K1003/1
Chief Investigator: Miss Amy Roe - 01892 515152 - aer10@canterbury.ac.uk
Local point of contact: Lizette Nolte - 02032225600 -Lizette.Nolte@eastlondon.nhs.uk
The aim is to investigate children's experiences of living with a parent with a psychotic mental health problem, using a qualitative approach. This will offer a rich descriptive and interpretive account, paying attention to the contradictions, complexity and context of young people's experiences. There will be a focus on exploring children's experiences of a parents' acute psychotic episode, which may include admission to hospital, the time following their return home and recovery.
As well as exploring the challenges that these children face I hope the research will redress the current imbalance in the literature by exploring any positive aspects to adolescents' experiences, their strengths, resources and competencies. I hope to develop a better understanding, to enable clinicians to offer more helpful and supportive services, as well as strengthening families existing resources.
- What is the young person's experience when a parent has an acute psychotic episode?
- What is the young person's experience of their parent's return from hospital and recovery from a serious episode?
- How do young people make sense of their parent's mental illness?